Turkish Journal of Plastic Surgery

REVIEW ARTICLE
Year
: 2021  |  Volume : 29  |  Issue : 5  |  Page : 38--43

A review of current developments in three-dimensional scaffolds for medical applications


Ufkay Karabay1, Resit Bugra Husemoglu2, Mehtap Yuksel Egrilmez1, Hasan Havitcioglu2 
1 Department of Molecular Medicine, Health Science Institute, Dokuz Eylul University, Izmir, Turkey
2 Department of Biomechanics, Institute of Health Sciences, Dokuz Eylül University, Izmir, Turkey

Correspondence Address:
Mr. Ufkay Karabay
Department of Molecular Medicine, Health Science Institute, Dokuz Eylul University, Izmir
Turkey

Humans require treatment due to the loss of tissues after trauma and diseases. Tissue engineering is a growing field of engineering and medical science to restore, maintain, or improve function of damaged or diseased tissues. The use of three-dimension (3D) scaffolds in particular offers a potential option for patients with tissue deficiency. Polylactic acid (PLA), poly-caprolactone (PCL), polyether-ether-ketone (PEEK), and thermoplastic polyurethane (TPU) are biomaterials that are commonly used in tissue engineering. Their applications of pure material or composite and supportive materials are of great importance for clinical practices. This review provides information on biomaterials and major areas of application and discusses their advantages and disadvantages against each other. The literature search from the database PubMed was done for the key words 3D PLA, PCL, PEEK, and TPU separately and 2029 articles were identified. These articles were limited according to clinical, in vivo and observational studies published in English and 140 articles were evaluated for this review. We selected the main articles according to the current data of 3D scaffolds and identical articles were removed. Fifty articles were included in the review. Many studies have reported the advantages of 3D scaffolds with composite or supplement materials over pure materials in the medical treatment. The advances in the development of new 3D scaffolds hold great promise for the prospective applications in the medical treatment.


How to cite this article:
Karabay U, Husemoglu RB, Egrilmez MY, Havitcioglu H. A review of current developments in three-dimensional scaffolds for medical applications.Turk J Plast Surg 2021;29:38-43


How to cite this URL:
Karabay U, Husemoglu RB, Egrilmez MY, Havitcioglu H. A review of current developments in three-dimensional scaffolds for medical applications. Turk J Plast Surg [serial online] 2021 [cited 2022 May 25 ];29:38-43
Available from: http://www.turkjplastsurg.org/article.asp?issn=1300-6878;year=2021;volume=29;issue=5;spage=38;epage=43;aulast=Karabay;type=0