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CASE REPORT
Year : 2018  |  Volume : 26  |  Issue : 1  |  Page : 37-39

A rare cause of squamous cell carcinoma which develops at an early age: Epidermodysplasia verruciformis


Department of Plastic, Reconstructive and Aesthetic Surgery, Selcuk University, Konya, Turkey

Correspondence Address:
Dr. Seyda Guray Evin
Department of Plastic, Reconstructive and Aesthetic Surgery, Selcuk University, Faculty of Medicine, Konya
Turkey
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/tjps.tjps_9_18

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Epidermodysplasia verruciformis (EV) (Lewandowsky–Lutz syndrome) is a genodermatosis that accommodates premalignant skin lesions extensively infected with human papillomavirus with underlying cellular and humoral immune disorders. Localized especially in regions extensively exposed to the sun such as the forehead, these skin lesions may turn into malignant lesions with the mutation-inducing effect of ultraviolet lights. The skin lesions that may emerge as a result of this transformation include actinic keratosis, Bowen's disease, squamous cell carcinoma (SCC), and more rarely basal cell carcinoma. The SCC that develops in patients with EV may act aggressively and can become locally invasive. This article aims at presenting the underlying EV as a rare etiological cause in patients with SCC at an early age.


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